Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy
Status:
Completed
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
Women undergoing surgical menopause often experience marked menopausal side effects but are
reluctant to use estrogen or other female hormones to ease the transition to menopause
because of worries that the hormones may increase breast cancer risks. This study will
evaluate tibolone in women experiencing surgical menopause to assess its effects on bone
health, menopause symptoms and breast density.
Phase:
Phase 2
Details
Lead Sponsor:
Dana-Farber Cancer Institute
Collaborators:
Beth Israel Deaconess Medical Center Brigham and Women's Hospital Massachusetts General Hospital United States Department of Defense