Effects of Vitamin B12 Treatment in Singers

• Status: Completed
• Trial end date: 2019-04-01
• Target enrollment: 0
• Participant gender: All

Summary

In this study, the investigators aim to assess if vitamin B12 treatment demonstrates a beneficial effect on voice performance. If so, they wish to examine the relationship between the vitamin B12 treatment and the study participant's general well-being.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Southern California
• Treatments: Hydroxocobalamin; Vitamin B 12; Vitamin B Complex; Vitamins

Criteria

Inclusion Criteria:

• Aged 18 to 65 years old

• An active singer who is presently singing

• Willing and able to comply with the study requirements

• Completed and signed an informed consent form.

Exclusion Criteria:

• Known vitamin B12 deficiency

• Active or recent vitamin B12 treatment (the subject must not receive vitamin B12 treatment for at least 4 weeks)

• Any known bleeding disorder

• Any known laryngeal pathology

• Plans to start any new treatment, oral/parenteral anticoagulant, supplement, or medication during the study period

• Scored above the highest 10 percentile of performance in all three voice evaluation questionnaires will be withdrawn from the study before the first injection (i.e., scored less than or equal to 7 in the Voice Fatigue Index (VFI), less than or equal to 6 in the Evaluation of the Ability to Sing Easily (EASE), and less than or equal to 4 in the Singing Voice Handicap Index 10 (SVHI-10))