Effects of Vitamin B12 on the Body's Internal Clock

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Circadian rhythms are 24-hour cycles that influence natural functions in the body such as heart rate, blood pressure, and body temperature. Circadian rhythms provide the body with an internal clock and affect sleep patterns. The purpose of this study is to determine the effects of vitamin B12 supplements on circadian rhythms and sleep-wake regulation.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Brigham and Women's Hospital
• Collaborator: National Center for Complementary and Integrative Health (NCCIH)
• Treatments: Hydroxocobalamin; Vitamin B 12; Vitamin B Complex; Vitamins

Criteria

Inclusion Criteria:

• Diagnosis of delayed sleep phase syndrome OR self-described as a "night owl"

Exclusion Criteria:

• History of medical illness

• History of psychiatric illness in participant or his or her family members

• Current medication or vitamin use

• Follow a vegan diet

• Significant visual problem

• Recent travel across time zones

• History of rotating shiftwork