Effects of Yangxinshi Pills on the Exercise Tolerance of the Patients With Coronary Heart Disease

• Status: Unknown status
• Trial end date: 2020-08-25
• Target enrollment: 0
• Participant gender: All

Summary

Compared with conventional treatment of the coronary heart disease,the aim of the research is to find out if the addition of Yangxinshi pills on the basis of conventional treatment can improve exercise tolerance of patients with coronary heart disease, improve quality of life or restore social function and mental health

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Affiliated Hospital of Changchun University of Chinese Medicine
• Treatments: Nitroglycerin

Criteria

Inclusion Criteria:

• Age 40 ~ 75, gender is not limited

• Have a clear history or ECG of hospital myocardial infarction , diagnosed as coronary heart disease by imaging diagnosis

• Sign the informed consent voluntarily

Exclusion Criteria:

• History of hospitalization for acute coronary syndrome in past 3 months

• Uncontrolled grade 3 hypertension（≥180/100mmHg）or hypotension（<90/60mmHg）

• History of stroke (cerebral hemorrhage, subarachnoid hemorrhage, cerebral thrombosis, cerebral embolism and stroke of unknown type) or lower extremity arterial disease in the past 6 months

• In past 6 months, have medical history of: pregnancy, prepare or suspected of pregnancy, abortion, breastfeeding or after childbirth

• Combined episode bronchial asthma or chronic obstructive pulmonary disease, bradycardia (resting heart rate <60bpm) or atrioventricular block

• Severely allergic constitution, known or likely to be allergic to the test drug or its components

• Known bleeding tendency or hemorrhagic disease

• Patients with severe liver and kidney dysfunction (creatinine clearance ≤ 40ml / min or in the active stage of kidney disease, serum aminotransferase ≥ 2 × upper limit of clinical reference), other life-threatening serious primary or psychiatric diseases and malignant tumors

• Any other situations that researchers believe may affect the clinical research