Effects of rhBNP in Pediatrics After Corrective Repair of Tetralogy Of Fallot

• Status: Completed
• Trial end date: 2019-07-20
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effects of rhRNP on urine output and hemodynamics following corrective repair of Tetralogy Of Fallot.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Jiao Tong University School of Medicine
• Treatments: Diuretics; Natriuretic Peptide, Brain

Criteria

Inclusion Criteria:

• Signed informed consent obtained from patient's legally acceptable representative.

• Pediatric patients after Repair of Tetralogy Of Fallot.

Exclusion Criteria:

• Psychotic, addictive or other disorder limiting the ability to provide informed consent or to comply with study requirements.

• Treatment or planned treatment with another investigational drug within 3 months of screening.

• Known hypersensitivity to bosentan or any of the excipients

• cardiogenic shock and inclination of hypotension（SBP< 60mmHg）.