Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement
Status:
Completed
Trial end date:
2010-04-26
Target enrollment:
Participant gender:
Summary
This novel compound is a new experimental treatment that may help people to stop compulsive
overeating. Compulsive overeating or binge eating is one of the main reasons why people are
overweight or obese. Recent research has shown that some kinds of overeating may be linked to
a brain chemical called dopamine. There is some evidence that blocking the action of this
chemical in animals can reduce food intake, particularly of foods that are high in fat and
sugar. The purpose of this study is to find out if this compound (which blocks the effects of
dopamine) has the same effect in overweight or obese people, as it does in animals.