Efficacy Comparison Study of Steroids to Control Post-operative Inflammation

• Status: Unknown status
• Trial end date: 2015-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Phacoemulsification is a quick method with less complication for cataract surgery. Due to the use of ultrasonic energy, it produced more post-operative inflammation than other methods. Many routes of steroid had been used to control post-operative inflammation. The investigators here compare the efficacy of single depot steroid subtenon injection (20-mg triamcinolone) with four-time-a-day steroid eye drop (0.1% dexamethasone) in controlling inflammation after uneventful phacoemulsification.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ophthalmic Solutions; Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

• Age older than 18 years old

• Uncomplicated cataract patient scheduled for phacoemulsification and posterior chamber intraocular lens implantation

• No History of prior intraocular procedures or any eye diseases such as uveitis, glaucoma, diabetic retinopathy

• No History of systemic autoimmune diseases

• No History of allergy to corticosteroids or to any component of the study medications

• No History of using corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs), or immunomodulating agents within 3 months prior to surgery

Exclusion Criteria:

• Complications occurred during cataract surgery such as ruptured posterior capsule, vitreous loss, or dropped nucleus

• Pregnant and lactating women