Efficacy Of Doxycycline & Versus Rifampin In Treatment Of Rhinoscleroma

• Status: Not yet recruiting
• Trial end date: 2023-07-31
• Target enrollment: 0
• Participant gender: All

Summary

The study is conducted To evaluate the Efficacy of Doxycycline (alone and in combination with Ciprofloxacin) as an alternative to the regular regimen in treating rhinoscleroma, especially for cases with contraindication to the use of one or more of the regularly used drugs.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Ciprofloxacin; Doxycycline; Rifampin

Criteria

Inclusion Criteria:

• Patients will be included after confirmation by histopathological examination.

• Patients presented in active stages of the disease.

• Patients between 18-70 years.

Exclusion Criteria:

• Any granulomatous lesion or features suggestive of rhinoscleroma associated with any other nasal lesions like syphilis, leprosy and tuberculosis were excluded.

• Patients below 18 years and above 70 years.

• Biopsy-negative cases.

• Patients in Atrophic or Sclerotic Stages of the disease.