Efficacy, Safety and Pharmacokinetics of Tinzaparin During Slow Low Efficient Daily Dialysis in Intensive Care Patients
Status:
Recruiting
Trial end date:
2025-12-31
Target enrollment:
Participant gender:
Summary
This study evaluates the pharmacokinetics of tinzaparin during renal replacement therapy
(RRT).
60 patients with clinical indication for pharmacological thromboprophylaxis and slow low
efficient daily dialysis (SLEDD) will be studied in Tampere University Hospital. All subjects
will receive a 4500 IU bolus of tinzaparin. The subjects in study group (n=30) will also
receive a 4500 IU continuous infusion of tinzaparin.