Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies
Status:
Recruiting
Trial end date:
2021-05-10
Target enrollment:
Participant gender:
Summary
Severe forms of scabies (crusted scabies and profuse scabies) require a specific treatment.
Ivermectin is a recommended treatment in common forms of scabies and represents a promising
treatment in crusted scabies in case reports. However, response to ivermectin remains
variable among studies, and there is no consensus on the schemes to adopt (dosages and
administrations). Ivermectin at 400 µg/kg has already been used, without showing toxicity (in
head lice treatment in particular). Investigators propose to demonstrate that 400µg/kg
ivermectin dosage will show better efficacy than a 200µg/kg in patients with severe forms of
scabies (crusted and profuse).