Efficacy Study in Allergic Rhinitis Patients After Intranasal Administration of AZD8848

• Status: Completed
• Trial end date: 2012-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary purpose of this study is to investigate effect, tolerability and safety of different dosing regimens of AZD8848 administered intranasally to seasonal allergic rhinitis patients out of season in an allergen challenge model.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: AstraZeneca
• Treatments: Adenosine

Criteria

Inclusion Criteria:

• Seasonal allergic rhinitis patients out of pollen season

• Have a history and presence of birch and/or timothy grass pollen induced seasonal allergic rhinitis for at least the previous 2 years (verified by a positive skin prick test)

• Patients with need of treatment for their nasal symptoms during the pollen season

Exclusion Criteria:

• Symptomatic perennial allergic or non-allergic rhinitis

• Family history of autoimmune disease A history of asthma