Efficacy Study of Genexol-PM and Cisplatin in Locally Advanced Head and Neck Cancer

• Status: Completed
• Trial end date: 2017-08-31
• Target enrollment: 0
• Participant gender: All

Summary

This clinical trial is Phase II trial for evaluating efficacy of induction chemotherapy using Genexol-PM + cisplatin for locally advanced head and neck cancer. The investigators try to evaluate response rate of Genexol-PM + cisplatin chemotherapy, and safety profile.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Collaborator: Clinical Research Center for Solid Tumor, Korea
• Treatments: Cisplatin

Criteria

Inclusion Criteria:

• locally advanced head and neck squamous cell carcinoma

• oral cavity, oropharynx, hypopharynx, larynx

• measurable lesion

• unresectable

• age 18 or more

• ECOG 0 or 1

Exclusion Criteria:

• distant metastasis

• pregnancy

• prior chemotherapy or radiation therapy

• 2ndary malignancy

• other unfit medical condition