Efficacy Study of Herbal Formula CUF2 to Treat Childhood Asthma
Status:
Completed
Trial end date:
2003-08-01
Target enrollment:
Participant gender:
Summary
Asthma is a long-term disease process with genetic, allergic, environmental, infectious,
emotional and dietary influences. The symptoms control are mainly using an inhaled drug,
avoiding triggers or taking preventive medicine. Although side effects are unlikely at low
dose of the asthma treatment, they have become apparent at the higher dose. Due to safety
concern, parents often turn to complementary and alternative medicine which they believe is
natural and safe and may help to reduce the conventional medication dosage.
There are number of reports that treatment with traditional Chinese herbs or formulas
resulted in significant improvement in lung function and reduction in the airway
hyper-reactivity reaction. Our study drug CUF2, was based on a classical formulae and had
been proven to have anti-inflammatory and immunomodulatory activities in laboratory and
animal studies.
With the pre-clinical evidence, this study aims to determine the effect of CUF2 on improving
the clinical symptoms, biochemical markers, and requirement of steroid dosage among children
with asthma.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Chinese University of Hong Kong
Collaborators:
Tuen Mun Hospital University Grants Committee, Hong Kong