Overview

Efficacy Study of IV Ibuprofen vs IV Acetaminophen Post Surgical Extraction

Status:
Unknown status
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
This study will compare how effective a single dose of an intravenous (IV) ibuprofen is when compared to single dose of IV acetaminophen in reducing pain. We will administer this study medication thirty minutes prior to removal of wisdom teeth. We want to see if administering these drugs prior to surgery may reduce post-operative pain. Administration of nonsteroidal anti-inflammatory drug before the onset of inflammation during surgery will reduce postoperative pain following third molar extraction when compared to the acetaminophen group. Subjects receiving nonsteroidal anti-inflammatory drug will consume less opioid medications compared to those receiving preemptive acetaminophen.
Phase:
Phase 2
Details
Lead Sponsor:
Tufts University School of Dental Medicine
Treatments:
Acetaminophen
Ibuprofen