Efficacy Study of Ketamine for Postoperative Pain in Opioid Dependent Patients

• Status: Completed
• Trial end date: 2012-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients who are dependent on opioids often have poor pain relief after major surgery. This study tests the hypothesis that adding intravenous ketamine to a postoperative regimen of intravenous opioids for postoperative pain will improve pain relief in this subset of patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Brigham and Women's Hospital
• Treatments: Analgesics, Opioid; Hydromorphone; Ketamine

Criteria

Inclusion Criteria:

• Chronic pain > 6 months

• Long term use of opioids

• Major surgery

Exclusion Criteria:

• Use of regional anesthetic techniques

• No need for intravenous (IV) patient controlled analgesia (PCA) after surgery