Efficacy Study of Prophylaxis With Fosfomycin Versus Ciprofloxacin Prior Prostate Biopsy

• Status: Completed
• Trial end date: 2016-01-25
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this clinical trial is compare the incidence of symptomatic or asymptomatic bacteriuria after transrectal ultrasound guided prostate biopsy using a single dose of fosfomycin 3 g one hour before the biopsy compared to observed with the use of a single dose of ciprofloxacin 500 mg 1 hour before biopsy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
• Collaborators: Hospital General Universitario Los Arcos del Mar Menor; Hospital General Universitario Santa Lucía
• Treatments: Ciprofloxacin; Fosfomycin

Criteria

Inclusion Criteria:

• Age > 18 years

• Patients with prostate-specific antigen (PSA) values >4 ng/ml or presenting either abnormality in rectal examination

• Patients who accept to participate in the study signing the consent informed form

Exclusion Criteria:

• Allergy to anyone of the study drug

• Intolerance to anyone of the study drug

• Urinary infection with positive uroculture

• Clinical finds suggesting infections

• Antimicrobial treatment during the las 4 weeks

• Patients with vesicle catheter

• Patients in dialysis

• Patients in hemodialysis