Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate and compare treatment with fiber and loperamide for fecal incontinence.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: US Department of Veterans Affairs; VA Office of Research and Development
• Treatments: Antidiarrheals; Calcium polycarbophil; Loperamide; Psyllium

Criteria

Inclusion Criteria:

• weekly fecal incontinence

Exclusion Criteria:

• fecal impaction

• inability to complete a baseline 1-week bowel diary

• rectal prolapse

• any prior radiation to the pelvis

• colo-rectal cancer

• rectal fistula

• inflammatory bowel disease

• neurological diseases (spinal cord injury, multiple sclerosis, Parkinson's disease)

• constipation (<2 bowel movements/week) or total colectomy