Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Chronic Graft Versus Host Disease
Status:
Unknown status
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
The primary purpose of the study is to evaluate the safety and efficacy of mesenchymal stem
cells (MSC) for the treatment of patients who have developed an extensive chronic graft
versus host disease (with skin and/or liver damage) after HSCs transplantation and do not
respond to first-line therapy.
The secondary purpose of the study is to evaluate the effect of mesenchymal stem cells (MSC)
on one-year survival rate, long-term survival rate, life quality and recurrence of patients
who have developed an extensive chronic graft versus host disease (with skin and/or liver
damage) after HSCs transplantation and do not respond to hormone treatment.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Chinese Academy of Medical Sciences
Collaborators:
307 Hospital of PLA Chinese PLA General Hospital Peking Union Medical College Zhejiang University