Efficacy and Safety Study of Calcipotriol Betamethasone Plus Calcipotriol in Sequential Therapy to Psoriasis

• Status: Completed
• Trial end date: 2014-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Evaluate the efficacy and safety of Calcipotriol Betamethasone Ointment and Calcipotriol Ointment in sequential therapy

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Xijing Hospital
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate; Calcipotriene; Calcitriol

Criteria

Inclusion Criteria:

1. Subjects who signed Informed Consent Form；

2. Male or female subjects 18-65 years of age；

3. Clinically confirmed diagnosis of plaque psoriasis as per the diagnostic criteria for psoriasis vulgaris specified in Clinical Dermatology.

4. Involved area 1-10% of the body surface area.

Exclusion Criteria:

1. Incompliance with the diagnosis of plaque psoriasis or plaque area > 10% of the body surface area.

2. Erythrodermic psoriasis, psoriasis arfhropathica or pustular psoriasis;

3. Known allergy to any component of the test or control drug；

4. Concomitant allergic skin disease such as eczema， contact dermatitis and urticaria, or other serious and/or extensive skin disease；

5. Systemic medication or ultraviolet therapy for psoriasis within 4 weeks prior to study initiation；

6. Topical use of external drug for psoriasis within 2 weeks prior to study initiation；

7. Women of child-bearing potential who are pregnant, plan to become pregnant during study or are lactating；

8. Glucocorticoid or immunodepressant, or hypoleukemia due to tumor or chemotherapy within the last 4 weeks；

9. Serious life-threatening condition that allows a life expectancy of less than 2 months；

10. Inability to guarantee taking medications and completing visits as scheduled during the study;

11. Serious infection that is not suitable for external treatment；

12. Any other condition that the investigator deems unsuitable for entering the study.