Efficacy and Safety Study of Concurrent Chemoradiation Therapy to Treat Locally Advanced Cervical Cancer
Status:
Terminated
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
Concurrent chemoradiation therapy with weekly cisplatin is the current standard treatment for
patients with locally advanced cervical cancer. However, weekly cisplatin is related to renal
toxicity and not convenient regimen. Recently, carboplatin has proved to be a good
radiosensitizer and less renal toxicity. Weekly carboplatin is more convenient regimen for
both patients and physicians. Weekly carboplatin may have similar efficacy with weekly
cisplatin and may have more favorable toxicity profile. Therefore, the investigators aimed to
evaluate the efficacy and safety of concurrent chemoradiation with weekly carboplatin in
patients with locally advanced cervical cancer.