Overview

Efficacy and Safety Study of an Antiarrhythmic Drug to Treat Atrial Fibrillation in Patients With Pacemakers

Status:
Completed
Trial end date:
2008-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to determine the safety and efficacy of an investigational antiarrhythmic drug (ATI-2042) in the treatment of atrial fibrillation in patients with a dual chamber pacemaker.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
ARYx Therapeutics
Criteria
Inclusion Criteria:

- Proven paroxysmal atrial fibrillation

- Pacemaker with appropriate AF diagnostics and recording capabilities

Exclusion Criteria:

- Known allergy to Amiodarone or previous treatment for severe Amiodarone toxicity

- Cardioversion within one month of screening

- Severe left ventricular dysfunction or CHF with NYHA Class III or above