Efficacy and Safety of Acetaminophen in Postoperative Pain Management of Infants
Status:
Recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
Pain will bring early and long-term adverse reactions to infants. The investigators need to
pay attention to whether there is pain in infants after surgery. Since infants cannot
self-report pain,The investigators need to use appropriate pain assessment scale to evaluate
the pain of these infants, so as to understand the status of postoperative pain in children.
The result of pain score not only enables investigators to understand the pain status of
children, but also helps investigators to give corresponding intervention and treatment
according to the pain degree of children. Postoperative pain management is one of the core
contents of ERAS. Effective pain management is beneficial to the early postoperative recovery
of infants and reduces the adverse reactions caused by pain. Sveral studies have confirmed
that the combination of acetaminophen and opioids could reduce the use of opioids after
surgery. But even if opioid use is reduced, it still causes many side effects for children.
This study evaluated the safety and efficacy of acetaminophen alone for postoperative
analgesia in infants.