Efficacy and Safety of Botulinum Toxin A for the Treatment of Refractory Overactive Bladder.
Status:
Completed
Trial end date:
2010-04-01
Target enrollment:
Participant gender:
Summary
Overactive bladder induce urgency, urge incontinence, nocturia and pollakiuria. This
condition is often resistant to anticholinergic drugs used as a first line treatment for this
purpose. Moreover muscarinic side effects (constipation, mouth dryness) often limits the use
of those treatments. This study is designed to evaluate the efficacy and safety of botulinum
toxin A injected into the detrusor muscle to control symptoms and improve quality of life for
patients resistant or intolerant to anticholinergic drugs.
Phase:
Phase 2
Details
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA