Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment in Psoriasis Vulgaris on the Face and Skin Folds
Status:
Completed
Trial end date:
2010-01-01
Target enrollment:
Participant gender:
Summary
There are few therapies suitable for the treatment of psoriasis on the face and skin folds.
As these areas are sensitive, irritation and other adverse reactions are more common than
elsewhere on the body. The purpose of the study is to compare the efficacy and safety of once
daily treatment for up to 8 weeks of an ointment containing calcipotriol 25 mcg/g plus
hydrocortisone 10 mg/g with calcipotriol 25 mcg/g in the ointment vehicle, hydrocortisone 10
mg/g in the ointment vehicle and the ointment vehicle alone in patients with psoriasis
vulgaris on the face and on the intertriginous areas (= double-blind phase). Furthermore, the
safety and efficacy will be evaluated for up to 60 weeks treatment as required of
calcipotriol 25 mcg/g plus hydrocortisone 10 mg/g ointment in psoriasis vulgaris on the face
and intertriginous areas (= open-label phase).