Overview

Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation

Status:
Terminated
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
This is an open-label analysis that will compare eculizumab versus Plasmapheresis (PP) and Immunoglobulin (IVIg) for the treatment of antibody-mediated rejection (AMR) in renal transplant recipients. All patients will be evaluated from the time of AMR diagnosis for 12 months.
Phase:
Phase 2
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborator:
Alexion Pharmaceuticals
Treatments:
Antibodies
Eculizumab
Immunoglobulins
Immunoglobulins, Intravenous