Overview

Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral Stenosis

Status:
Recruiting
Trial end date:
2026-05-20
Target enrollment:
Participant gender:
Summary
This study aims to compare the efficacy and safety of the edoxaban and the warfarin in atrial fibrillation patients with mitral stenosis. The study design is a multicenter, randomized, open-label, investigator initiated phase 2 trial. The patients were randomly assigned to Edoxaban or Warfarin groups. Primary outcome was a composite of stroke and systemic arterial thromboembolism. The safety outcome was major bleeding.
Phase:
Phase 2
Details
Lead Sponsor:
Sung-Hwan Kim
Collaborator:
Daiichi Sankyo Korea Co., Ltd.
Treatments:
Edoxaban
Warfarin