Overview

Efficacy and Safety of Fruquintinib in Combination With Sintilimab in Advanced Renal Cell Carcinoma

Status:
Not yet recruiting
Trial end date:
2025-03-01
Target enrollment:
Participant gender:
Summary
The study consists of two parts, the first part is a randomized, open-label, active-controlled study to evaluate the efficacy and safety of Fruquintinib in combination with Sintilimab versus axitinib or everolimus montherapy as second-line treatment for locally advanced or metastatic renal cell carcinoma. The second part is a Fruquintinib montherapy factorial cohort study to evaluate the efficacy and safety of Fruquintinib monotherapy as for second-line treatment of locally advanced or metastatic renal cell carcinoma.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Hutchison Medipharma Limited
Treatments:
Axitinib
Everolimus