Efficacy and Safety of GTN vs. Nifedipine in Acute Anal Fissure: A Clinical Trial
Status:
COMPLETED
Trial end date:
2025-05-10
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare the therapeutic efficacy and safety profile of Glyceryl Trinitrate (GTN) and Nifedipine ointments in the treatment of acute anal fissures in adults. The main questions it aims to answer are:
Which ointment is more effective in promoting fissure healing and symptom relief? What are the adverse effects associated with each treatment? Researchers will compare GTN and Nifedipine ointments to determine which provides better symptom resolution with fewer side effects.
Participants will:
Apply GTN or Nifedipine ointment topically twice daily for four weeks Attend follow-up visits for symptom assessment and adverse effect monitoring
Phase:
PHASE4
Details
Lead Sponsor:
Hafiz Muhammad Hamza
Collaborator:
Federal Government Polyclinic (Postgraduate Medical Institute)