Efficacy and Safety of Hourly Titrated Misoprostol Versus Vaginal Dinoprostone and Misoprostol for Cervical Ripening and Labor Induction

• Status: Unknown status
• Trial end date: 2020-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study evaluates the efficacy and safety of the administration of oral misoprostol versus vaginal dinoprostone and vaginal misoprostol for cervical ripening and labor induction.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oihane Lapuente Ocamica
• Treatments: Dinoprostone; Misoprostol

Criteria

Inclusion Criteria:

• Women over 18

• single pregnancy

• cephalic presentation

• intact membranes

• unfavorable cervix ( less than 6 Bishop )

• CTGR not reactive decelerative

• Signed informed consent by the patient.

Exclusion Criteria:

• prior Cesarean section or previous uterine surgery .

• Allergy or intolerance to any of the study drugs

• stillbirth

• uterine growth restricted fetuses

• contraindication for vaginal delivery

• Anterior placenta

• Multiparity

• moderate to severe heart disease

• hypertensive disorders of pregnancy

• Suspected chorioamnionitis

• Coagulation disorders

• history of epileptic seizures

• liver or kidney disease

• Cognitive impairment or bad knowledge of Spanish