Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain
Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to compare the efficacy of a combination product
containing ibuprofen 400 mg and caffeine 100 mg versus either ingredient alone as well as
placebo for the treatment of post-surgical dental pain over an eight-hour period followed by
a single dose of study medication (study stage 1). A secondary objective is to evaluate
efficacy of multiple doses of the combination in comparison to ibuprofen alone over a 5-day
post-surgical period (study stage 2).