Efficacy and Safety of Quadruple Therapy in Eradication of H. Pylori: A Comparison to Triple Therapy
Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
This study aims at evaluating efficacy and safety of quadruple therapy (bismuth,
metronidazole, tetracycline and omeprazole: OBMT) vs triple therapy (amoxicillin,
clarithromycin and omeprazole: OAC) in H. Pylori eradication. It is hypothesized that
quadruple therapy will be comparable in efficacy to triple therapy. Subjects with confirmed
H. pylori positive status will be randomized to one of the treatments described above. At
week 6 and 10 follow-up visits, a urea breath test (UBT) will be performed to confirm
eradication.