Overview

Efficacy and Safety of Rabbit Antithymocyte Globulin 3mg/kg in Kidney Transplant Patients Under Steroid-free and CNI Minimization Maintenance Immunosuppressive Regimen

Status:
Unknown status
Trial end date:
2020-01-01
Target enrollment:
0
Participant gender:
All
Summary
Single-center, prospective, randomized, open-label clinical trial to evaluate the 1-year efficacy and safety of rATG 3mg/kg compared to 6mg/kg in low to moderate immunological risk patients receiving low exposure tacrolimus plus everolimus (EVL) in a steroid-free protocol.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hospital Geral de Fortaleza
Treatments:
Antilymphocyte Serum
Immunosuppressive Agents
Thymoglobulin
Criteria
Inclusion Criteria:

- Primary kidney transplant recipients, adults

Exclusion Criteria:

- PRA > 50%

- DSA > 1500 MFI

- Retransplantation

- Patients who are planning to receive mycophenolate instead of everolimus

- Patients who have planning for follow-up in another center