Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol Intramuscular (IM) Injection for Treatment of Acute Psychotic Agitation in Schizophrenia

• Status: Completed
• Trial end date: 2009-03-01

Summary

This is a multi-centre, open, randomized, haloperidol-referenced, 47 days two treatment sessions, parallel-group study.

After screening period, eligible subjects will be entered 5 days treatment session I to compare the efficacy between risperidone oral solution combination clonazepam oral and haloperidol IM injection on controlling psychotic agitation, then will be followed by 6 additional weeks treatment session II for exploring the effect of medicine switching from IM injection to oral.

• Phase: Phase 4

Details

• Lead Sponsor: Central South University
• Collaborators: Capital Medical University; Chongqing Mental Hospital; Guangzhou Mental Hospital; Shanghai Mental Health Center; Wuhan Mental Health Institute
• Treatments: Clonazepam; Haloperidol; Haloperidol decanoate; Pharmaceutical Solutions; Risperidone