Efficacy and Safety of Short-term Postoperative Anticoagulant Therapy to Prevente Thrombosis in Arterovenous Fistula

• Status: Unknown status
• Trial end date: 2020-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Many guidelines at home and abroad advocate that arteriovenous fistula should be the first choice of permanent vascular access, but it is easy to form thrombus in a short time after arteriovenous fistula molding, resulting in internal fistula stenosis or occlusion. In this study, the investigators plan to screen the patients with arteriovenous fistula in the blood purification center of our hospital. Through the study design of random grouping and open label, the investigators will discuss the use of low molecular weight heparin or warfarin to prevent thrombosis in a short period of time after arteriovenous fistula operation. According to the research results, the investigators will understand efficacy and safety of short-term postoperative anticoagulant therapy to prevente thrombosis in arterovenous fistula.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: First Affiliated Hospital of Chongqing Medical University
• Treatments: Anticoagulants; Calcium heparin; Dalteparin; Heparin; Heparin, Low-Molecular-Weight; Tinzaparin; Warfarin

Criteria

Inclusion Criteria:

• the participants were treated with autogenous arteriovenous fistula, reconstruction and balloon dilatation;

• stable health, compliant with treatment, and active following treatment. Exclusion Criteria.

• age > 85 years old;

• history of blood system diseases;

• history of familial and hereditary bleeding diseases;

• important complications affecting the coagulation system, such as liver diseases;

• abnormal coagulation function and active bleeding;

• history of intracranial and digestive tract bleeding, obvious skin stasis;

• complications, such as surgery and tumor, which significantly increase the risk of bleeding;

• no subjective will.