Efficacy and Safety of Valsartan/Amlodipine Compared to Amlodipine in Patients With Essential Hypertension
Status:
Completed
Trial end date:
2007-11-01
Target enrollment:
Participant gender:
Summary
This study was designed to compare the efficacy, tolerability, and safety of the combination
valsartan/amlodipine 160/5 mg versus amlodipine 10 mg in patients with essential hypertension
not adequately controlled (defined as mean sitting systolic blood pressure [msSBP] ≥ 130 mmHg
and ≤ 160 mmHg) on amlodipine 5 mg alone. The study evaluated both the efficacy and
tolerability of the treatments by providing data that assessed blood pressure and the
proportion of patients developing peripheral edema.