Efficacy and Safety of Valsartan Versus Amlodipine in Postmenopausal Women With Hypertension

• Status: Completed
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is compare treatment with valsartan with the possible addition of a diuretic, hydrochlorothiazide, on high blood pressure with the drug amlodipine with the possible addition of a diuretic, hydrochlorothiazide. In particular, the effect of treatment on the stiffness of the blood vessels will be studied.

• Phase: Phase 4

Details

• Lead Sponsor: Novartis
• Treatments: Amlodipine; Hydrochlorothiazide; Valsartan

Criteria

Inclusion Criteria:

• Postmenopausal women

• Mild to moderate hypertension

• Statin therapy or LDL≤ 4.1 mmol/L

Exclusion Criteria:

• Severe hypertension

• LDL > 4.1 mmol/L if not taking anti-hyperlipidemic medication

• Certain hormonal therapy

• History of stroke, myocardial infarction, heart failure, chest pain, abnormal heart rhythm

• Liver, kidney, or pancreas disease

• Diabetes

• Raynaud's disease or any other significant peripheral vascular disease

• Allergy to certain medications used to treat high blood pressure

Other protocol-defined inclusion/exclusion criteria may apply.