Efficacy and Safety of a Retinoid for the Treatment of Severe Chronic Hand Dermatitis

• Status: Completed
• Trial end date: 2007-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine the therapeutic effect of alitretinoin, a retinoid, on severe, therapy refractory chronic hand dermatitis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Basilea Pharmaceutica
• Treatments: Alitretinoin

Criteria

Inclusion Criteria:

• Chronic hand dermatitis, all types including hyperkeratotic, vesicular, fingertip dermatitis

• Lasting for 6 months since initial diagnosis

• Rated severe

• Refractory to standard therapy including non-medicated therapy and avoidance of irritants and allergens

• Refractory to topical steroids

Exclusion Criteria:

• Female patients who are pregnant or want to become pregnant

• Female patients of child bearing potential who cannot use or will not commit to using two effective forms of contraception simultaneously

• Patients whose disease is adequately controlled by standard non-medicated therapy and standard corticosteroid therapy