Efficacy of Alkalinized Lidocaine in the Endotracheal Tube Cuff on the Incidence of Coughing During Emergence

• Status: Completed
• Trial end date: 2014-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to compare the efficacy of endotracheal tube cuffs pre-filled with alkalinized lidocaine on the:

• incidence of coughing during emergence of general anesthesia

• time needed for emergence following a desflurane-based anesthesia

• incidence of sore throat after extubation.

The investigator's hypothesis is that the use of endotracheal tube cuffs pre-filled with alkalinized lidocaine will reduce the incidence of coughing by 50% relative to a control group following a desflurane-based anesthesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
• Collaborator: Centre de Recherche du Centre Hospitalier de l'Université de Montréal
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Patients undergoing elective short-duration surgery under general anesthesia (expected duration of less than 2 hours)

• Physical status 1-3

Exclusion Criteria:

• Asthma or severe pulmonary disease

• Pulmonary tract infection

• Anticipated difficult intubation

• Current use of cough medicine

• Contraindication to lidocaine

• Pregnancy

• Airway surgery

• Inability to provide informed consent

• Patient refusal