Overview Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome Status: Completed Trial end date: 2016-10-01 Target enrollment: Participant gender: Summary This study is designed to evaluate long term efficacy of intravenous bisphosphonates for bone marrow edema in patients with SAPHO syndrome. Phase: Phase 1 Details Lead Sponsor: Peking Union Medical College HospitalTreatments: DiphosphonatesPamidronate