Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence
Status:
Unknown status
Trial end date:
2010-07-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to assess the efficacy of caffeine compared to placebo as a
maintenance treatment for cocaine dependence. Caffeine potentiation with biperiden will be
also studied.
Ninety patients with snorted/sniffed cocaine dependence will be randomized to receive
caffeine (300 - 1200 mg t.i.d.) plus biperidene (8 mg b.i.d.) caffeine (300 - 1200 mg t.i.d.)
with placebo or placebo during 10 days in an in-hospital setting.
Phase:
Phase 4
Details
Lead Sponsor:
Hospital Universitari Vall d'Hebron Research Institute