Efficacy of Chronoterapy in Oral Surgery

• Status: Not yet recruiting
• Trial end date: 2021-12-20
• Target enrollment: 0
• Participant gender: All

Summary

Lower third molar extraction is one of the most common treatments in oral surgery practice. It is a treatment with inherent complications such as postoperative pain, swelling or trismus. In order to minimize disconfort after extraction, analgesic and anti-inflammatory medication is prescribed. Recently, it is seen that circadian rhythm may play an important role on drugs metabolism, modulating its effect depending on the moment of administration. The aim of the study is to analyze if dosage modification of a Non Steroideal Anti-Inflammatory (ibuprofen) affects on postoperative pain, swelling and open mouth limitation comparing to the normal dosage.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universidad Complutense de Madrid
• Collaborator: McGill University
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

• Age between 18 and 35 years old

• Bilateral retained lower third molar

Exclusion Criteria:

• NSAID allergic

• Contraindication for surgical removal of third molar