Efficacy of Continuous Apomorphine Infusion on Cognitive and Neuropsychological Functions in Parkinson's Disease
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
In Parkinson's disease, treatment mainly aims to improve motor functions. However, other
dysfunctions are often observed in Parkinson's patients, and may have important consequences
on the quality of life of patients.
Cognitive and neuropsychological troubles may be observed, as memory impairment or anxiety
for example. As this kind of troubles is worrying for the patient himself (herself) and
his/her family, treatment needs to take into account those troubles in addition to motor
difficulties. In our centre, we have already used continuous Apomorphine infusions among
Parkinson's patients and it seems to have good results. The present study aims to objectively
assess the efficacy of continuous Apomorphine infusions on cognitive and neuropsychological
functions in Parkinson's disease using clinical and positron emission tomography (PET)-scan
measures.