Overview

Efficacy of Coreg CR and Lisinopril on Markers for Cardiovascular Functional and Structural Disease

Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
This study will examine the individual and combined effects of Coreg CR and lisinopril, on cardiovascular health as measured by Rasmussen Disease Score (RDS) in a blinded, placebo controlled comparison over a 9-month study period. Patients to be randomized will have pre-hypertensive blood pressures that do not require anti-hypertensive therapy and at least one additional cardiovascular risk factor.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Minnesota
University of Minnesota - Clinical and Translational Science Institute
Collaborator:
GlaxoSmithKline
Treatments:
Carvedilol
Lisinopril