Efficacy of Cyclic DSG Compared With Cyclic MPA for the Treatment of Anovulatory DUB

• Status: Unknown status
• Trial end date: 2018-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The objectives of the present study is to determine the effectiveness of cyclic desogestrel (DSG) compared with cyclic medroxyprogesterone acetate for the treatment of anovulatory dysfunctional uterine bleeding (DUB) in the following aspects:

1. Endometrial histopathology changes

2. Menstrual cycle control.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Desogestrel; Medroxyprogesterone; Medroxyprogesterone Acetate

Criteria

Inclusion Criteria:

• Premenopausal women with anovular DUB (proved by endometrial histology)

• Age > 18 yr.

Exclusion Criteria:

• Any uterine pathology that might cause abnormal uterine bleeding

• Contraindication to progestin treatment (such as breast cancer)

• Severe drug allergy towards a progestogen

• Intake of any hormonal treatment in the previous 3 months