Efficacy of Elidel Cream on Erosive Oral Lichen Planus

• Status: Completed
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate whether topical applied pimecrolimus will lead to improvement of erosive oral lichen planus. This effect will be monitored by reduction of erosive mucosal area and reduction of patient's pain symptoms.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Tuebingen
• Treatments: Pimecrolimus

Criteria

Inclusion Criteria:

• Clinically and histologically confirmed diagnosis of erosive oral lichen planus

• Spontaneous or meal related oral pain

• No topical therapy 2 weeks prior to study start

• No systemic therapy 4 weeks prior to study start

• Signed informed consent

Exclusion Criteria:

• Pregnant or breast-feeding women

• Known allergy to macrolide antibiotics

• Known current active malignant disease or in patient's history

• Known immunodeficiency or HIV infection

• Participation at another clinical trial within the last 6 months