Overview
Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial
Status:
Completed
Completed
Trial end date:
2008-03-01
2008-03-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitisPhase:
N/AAccepts Healthy Volunteers?
NoDetails
Lead Sponsor:
University of Texas Southwestern Medical CenterCollaborator:
AstraZenecaTreatments:
Esomeprazole
Criteria
Inclusion Criteria:- age between 18-80, symptoms of perennial rhinitis, negative epicutaneous skin testing
to a panel of common aeroallergens, and ability to speak English
Exclusion Criteria:
- pregnancy or breast-feeding, evidence of positive skin tests to a common aeroallergen,
treatment with a proton pump inhibitor within the month prior to enrollment, treatment
with any other anti-reflux therapy within the last month on a daily basis or within
the last two weeks on an as needed basis, and other gastrointestinal disorders leading
to reflux symptoms