Efficacy of Etoricoxib 60 mg in Modifying Pain Hypersensitivity in People With Knee Osteoarthritis
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
This study aims to better understand the way in which painful osteoarthritis affects
different people and whether an anti-inflammatory medication such as Arcoxia (etoricoxib) can
help to modify this pain. The study will use questionnaires and tests of pain sensitivity to
identify arthritis sufferers with more widespread, nerve-type pain and then to investigate
whether a daily dose of Arcoxia is more effective than a placebo pill in reducing these
symptoms and improving functional movements. The study will also be comparing the same test
results of a small group of subjects without knee pain.