Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the Treat
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
The primary objective of the study is to determine whether quetiapine extended-release in
combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo
in treating depressive and anxiety symptoms in patients with both major depression and
generalized anxiety disorder. Approximately 64 individuals (adults 18-65) will be randomly
assigned to treatment group for 16 weeks. Weekly CBT sessions will be conducted lasting about
45 minutes and weekly visits with the study psychiatrist lasting about 20 minutes in which
medication will be discussed. Both clinician administered and self-report measures will be
used to compare groups before and after 16 weeks.