Efficacy of Fentanyl to Reduce the Time of Severe Postoperative Pain Relief Compared to Morphine
Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
Fentanyl is a potent opioid, it is theoretically 100 times more potent that morphine and in
severe acute postoperative pain acts faster than its congener (morphine ) for pain relief .
In the literature there is no study that corroborates this theoretical assumption and
proposes to compare which has fewer adverse effects. This drug produces effects similar to
those reported for morphine but less magnitude and has the advantage that during the
postoperative period respiratory depression, antitussive effect , gastrointestinal discomfort
and physical dependence are manifested in a significantly less degree.
Trying to solve the management of postoperative pain relief , our objective is to determine
by controlled clinical trial of superiority if in adult patients undergoing surgery ,
fentanyl reduces faster qualification time of severe pain to mild pain in the postanesthesia
care unit compared to morphine.