Efficacy of Fibrinolytic Agents in Complicated Pleural Effusion
Status:
Unknown status
Trial end date:
2020-04-30
Target enrollment:
Participant gender:
Summary
Intrapleural administration of fibrinolytic therapy, urokinase in parapneumonic effusion and
empyema has been shown to decrease the need for surgical intervention and length of hospital
stay. Pleural adhesions are easily formed in the early stages of empyema and the thickening
of the pleural causes subsequent treatment difficulties. The goal of this study was to
observe and compare the efficacy of treatment in empyema patients with urokinase and chest
drainage or with chest drainage or with chest tube drainage alone so as to provide evidence
for guiding clinical treatment.